Abstract
Metastatic lesions to the oral cavity are uncommon and usually an evidence of widespread disease. The aim of this study is to report a case of mammary tumor metastasis with clinical findings mimicking bisphosphonate's osteonecrosis. A 75-year-old female patient, diagnosed with metastatic breast carcinoma for bones and previous history of osteonecrosis in the hard palate a year earlier, was referred to the Stomatology Department for evaluation of an oral painful lesion lasting 7 days. Intraoral examination revealed an ulcerated irregular lesion in the hard palate measuring 1-cm extension to previous bisphosphonate's osteonecrosis area. Diagnosis hypothesis were osteonecrosis and metastasis. The incisional biopsy was performed and, according to the histopathologic analysis and immunohistochemistry panel, the diagnosis of mammary lobular carcinoma metastasis was established. Currently, the patient is in treatment. Although rare, metastasis should be included as a differential diagnosis of oral lesions. This case emphasizes the importance of a multidisciplinary team in cancer treatment.
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