Abstract
BackgroundBreast cancer is the leading cause of cancer death in women, and most breast cancer related deaths are due to metastasis. Urinary bladder metastasis from breast cancer is rarely reported in the literature.Case presentationWe report a case of a 77-year-old female with history of left breast cancer, who presented a thickening of the bladder wall at pelvic ultrasound. Biopsy confirmed that the origin was lobular carcinoma of breast origin. The patient received chemotherapy, but the clinical course of the patient was very aggressive and she died one year later.ConclusionBladder metastasis from breast cancer is rare, but the literature reveals an increase in such occurrence over the last few years. Pathologic diagnosis relies on immunohistochemical studies. Chemotherapy and hormonal treatment represent the standard therapy, with radiotherapy being used only to control bladder bleeding. The prognosis is usually poor.
Highlights
ConclusionBladder metastasis from breast cancer is rare, but the literature reveals an increase in such occurrence over the last few years
Breast cancer is the leading cause of cancer death in women, and most breast cancer related deaths are due to metastasis
Bladder metastasis from breast cancer is rare, but the literature reveals an increase in such occurrence over the last few years
Summary
Bladder metastasis from breast cancer is scarce [21]. In view of the frequency of breast cancer, doctors should always consider unusual metastatic sites such as the bladder. Most bladder metastases occur in invasive lobular cancer [2]. It is important to conduct a radiological exploration and to provide a histological proof, preferably by performing transurethral resection. Chemotherapy and hormonal therapy are the cornerstone of management of this type of metastasis. Radiotherapy is usually reserved to control bleeding. The prognosis of bladder metastases is poor unless it represents the only metastatic site [2, 8]
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