Abstract
Three cases of metastatic disease in bone affected by Paget's disease are presented. The literature has been reviewed and a total of 26 similar cases found. The occurrence is rare compared to the frequency of sarcomatous transformation in Paget's disease, and low considering the frequency with which metastatic disease and Paget's disease each affect the elderly. This suggests that pagetic bone may resist the implantation of metastatic tumour cells.
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