Metanephric Adenoma of the Kidney: A Case Report and Literature Review

Muhammad Asykar Palinrungi,Prihantono Prihantono

doi:10.12691/ajmcr-5-9-5

Abstract

Metanephric Adenoma is a rare benign renal epithelial tumor, only a few reports are found in the literature. Reported a 48-year-old female with a palpable mass at left flank, pain and microscopic haematuria. Radiological imaging shows a mass on left Kidney suspected of Renal Cell Carcinoma. Transperitoneal left radical nephrectomy was done. Histopathological results revealed a Metanephric adenoma. The patient is repatriated from the hospital four days after surgery. The patient is in good health, and there is no sign of recurrence on 48 months follow up after surgery.

Highlights

Metanephric Adenomas referred to as "nephrogenic adenoma" or "embryonal adenoma," is a rare benign tumor, which clinically, clinical immunohistochemically and tumor histology of this tumor are unique [1,2,3]
Pages and Granier proposed the term nephrogenic nephroma in 1980 [3], regarded as adenomas by Mostofi et al in 1988 [4]. This type of tumor is only 0.2% of the Renal epithelial neoplasms [5], and so far less than 200 cases were documented in the world literature [6]. These tumors are derived from the primitive metanephric epithelium of the proximal nephron remainings
If there is still tissue left in renal parenchyma after birth, the tissue is likely to evolve into Wilms' tumor or sometimes develop into Metanephric adenoma

Summary

Introduction

Metanephric Adenomas referred to as "nephrogenic adenoma" or "embryonal adenoma," is a rare benign tumor, which clinically, clinical immunohistochemically and tumor histology of this tumor are unique [1,2,3]. Pages and Granier proposed the term nephrogenic nephroma in 1980 [3], regarded as adenomas by Mostofi et al in 1988 [4] This type of tumor is only 0.2% of the Renal epithelial neoplasms [5], and so far less than 200 cases were documented in the world literature [6]. These tumors are derived from the primitive metanephric epithelium of the proximal nephron remainings These tumors are associated with Wilms' tumor and another nephrogenic tumor; even it can be found simultaneously [1,2,4,7]. Knowledge of metanephric adenoma is essential in its management, in which resection has been proven effective in most cases [4,8,9]

Case Report

Findings

Discussion