Abstract
Chronic Chagas' disease comprises an indeterminate and a cardiac stage. Patients in the former have no clinical, electrocardiographic or radiologic abnormalities. However, 20 to 40% of these patients may have, as demonstrated by echocardiography, left ventricular wall motion abnormalities and normal systolic function [1,2]. Clinicians and researchers consider this particular stage as transitional and amenable to preventive treatment. Therefore, several investigations have been conducted to identify predictive biomarkers of progression of this disease.
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