Abstract
AbstractMetal‐free oxidative sulfonylation strategy for the direct incorporation of sulfonyl units to access 3‐sulfonyl succinimides, diarylmethyl sulfones and diarylsulfones via a free‐radical pathway under aerobic conditions in aqueous media has been developed. Using easily accessible sulfonyl source, this methodology proceeds efficiently with a high degree of functional group compatibility under operationally simple reaction conditions. In this novel transformation with moderate to excellent yield, a green reaction system is established without the risk of metal contamination and inert atmosphere at room temperature. Mechanistic investigations revealed that sulfonyl radicals could be generated in situ from sulfonyl hydrazides in the presence of I2/TBHP under aerobic conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
