Metal-organic framework-based sensors for the detection of toxins and foodborne pathogens

Abstract

Toxins and foodborne pathogens contamination induce adverse effects on human health and cause enormous economic losses. Therefore, reliable analysis methods are essential. Recently, with the achievements of nanoscience, metal-organic frameworks (MOFs), a novel class of porous crystalline materials, have received increasing interest in preparing sensors for toxins and pathogens analysis because of their intriguing properties, such as large surface area, high porosity, and diverse functionality. In this article, first, typical methods for MOF synthesis are presented. Then a brief introduction of some typical toxin and pathogens is given. Furthermore, recent progress in MOF-based sensors for the measurement of toxins and pathogens are summarized. Different electrochemical and optical sensors are outlined according to the roles of MOFs in sensor development and some typical examples are presented. Finally, challenges and future perspectives are discussed. • MOFs and MOF composites emerge as promising materials in sensing. • Recent developments of MOF-based sensors are summarized for toxins and pathogens detection. • Challenges and prospects of MOF-based sensors in toxins and pathogens analysis are proposed.