Abstract
AbstractA novel visible‐light‐induced radical cascade trifluoromethylation/cyclization of N‐benzamides with CF3SO2Na has been achieved. This protocol provides an efficient strategy for the synthesis of CF3‐containing isoquinoline‐1,3‐diones under mild reaction conditions. The reaction features metal‐free, air oxidation, CF3SO2Na as CF3 source, additives free and operational simplicity. Moreover, the representative products displayed significant potencial antifungal activities in vitro.
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