Metal‐free regioselective selenylation of β‐napthol derivatives promoted by trichloroisocyanuric acid

Abstract

AbstractA new approach for synthesizing selenylated naphthalene derivatives is described herein, employing trichloroisocyanuric acid (TCCA) as the oxidizing agent. The developed protocol yielded 18 compounds, with yields ranging from 32 % to 90 %. Additionally, the reaction was conducted under mild conditions, utilizing ethanol as the solvent at room temperature, demonstrating good atom economy. The key aspect of the protocol is the in situ generation of electrophilic selenium species through the reaction of diorganyl diselenides and TCCA.