Abstract
AbstractMetal‐free directed ortho C–H iodination of biaryl‐2‐carbonitriles was developed. A series of 2′‐iodobiaryl‐2‐carbonitriles were synthesized from substituted biphenylcarbonitriles and naphthylbenzonitriles in reasonably good yields by using bis(pyridine)iodonium(I) tetrafluoroborate (IPy2BF4, Barluenga's reagent) and HBF4·OEt2. The biaryl‐2‐carbonitriles are useful precursors for the synthesis of benzocyclic ketones.
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