Abstract
A metal-free, regioselective strategy for the synthesis of 3-arylimidazo[1,2-a]pyridines from β-nitrostyrenes and 2-aminopyridines using triethylamine as the catalyst and H2O2 (30% aq.) as the oxidant is reported. The use of an inexpensive base and facile reaction conditions make this strategy a practical alternative for the synthesis of 3-arylimidazo[1,2-a]pyridines.
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