Metal Complex–DNA Interactions

Abstract

A Basic Structural and Kinetic Aspects 1. Sequence-Selective Binding of Transition Metal Complexes to DNA 2. Thermodynamic Models of Metal Ion -DNA.Interactions 3. Metal Ion Coordination in G-quadruplexes 4. Supramolecular Chemistry of Metal-Nucleobase Complexes B Medical Applications 5. Platinum Drugs, Nucleotides, and DNA: the Role of Interligand Interactions, nucleotides and DNA 6. Role of DNA Repair in Antitumor Effects of Platinum Drugs 7. Telomeres and Telomerase: Potential Targets for Platinum Complexes 8. Toward Photodynamic Therapy of Cancer with Platinum Group Metal Polyazine Complexes 9. Platinated Oligonucleotides: Synthesis and Applications for the Control of Gene Expression 10. New Titanium and Ruthenium Anticancer Drugs and their Interaction with DNA C DNA-Recognition - Nucleases and Sensors 11. Groove-Binding Ruthenium(II) Complexes as Probes of DNA Recognition 12. DNA Recognition and Binding by Peptide-Metal Complex conjugate 13. Artificial Restriction Agents - Hydrolytic Agents for DNA Cleavage 14. New Metallo-DNAzymes: Fundamental Studies of Metal-DNA Interactions and Metal Sensing Applications 15. Two-metal Ion Dependent Catalysis in Nucleic Acid Enzymes D Toxicological aspects 16. Mercury- DNA Interactions. Structural Studies on Mercury II -Mediated T-T Base-Pair with NMR Spectroscopy 17. Chromium-Induced DNA Damage and Repair 18. Arsenic and nickel: Mechanisms Affecting DNA Integrity