Abstract
IT has been shown in this and other laboratories that the administration of glucagon will produce an intense but temporary diabetes in force-fed rats and in human subjects.1 2 3 However, a diabetes persisting after cessation of glucagon treatment has not been reported in any species. This paper is a preliminary account of investigations yielding evidence that when immature rabbits are treated with glucagon for a prolonged period a "metaglucagon diabetes" can be produced.Methods and ProceduresThe litters of three albino rabbits of mixed origin were used. Treatment was started on the third postnatal day. Nine of the animals received a . . .
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