Abstract
Metachronous Bilateral Breast Invasive Lobular Carcinoma with Metastasis to an Unusual Site
Highlights
Breast cancer is the most common malignancy in women and it is the second most common cause of cancer related deaths in women
Gastric metastasis from primary breast cancer is a rare phenomenon. It is more prevalent in the invasive lobular type of breast cancer, the most common histologic subtype of breast cancer is the invasive ductal type
The predominant histologic type of breast cancer with gastrointestinal (GI) metastases is a lobular type, which accounts for only 8% of all breast cancers. [6,7] Metastatic breast cancer is positive for CK7, GCDFP-15, carcinoembryonic antigen, ER and PR, and it is negative for CK20. [8,9] CK20 and CK7 expression are important markers
Summary
Breast cancer is the most common malignancy in women and it is the second most common cause of cancer related deaths in women. Gastric metastasis from primary breast cancer is a rare phenomenon. We present a case of breast cancer metastasis to the stomach. 44-year-old female, presented in February 2011 with complaints of left breast mass. There was a large mass in the left breast measuring 7×6 cm. Mammogram shows left breast mass measuring 3×4×7 cm. Trucut biopsy taken and histopathology was invasive lobular carcinoma. MRI breast done after neo-adjuvant chemotherapy showed no mass in the breast. MRM done and histopathology showed focal areas of invasive lobular carcinoma. CT scan chest-abdomen done showed right axillary lymphadenopathy, heterogenous left ovary, abdominal ascites, mesenteric stranding with lymphadenopathy and gastric wall thickening. Ultrasound guided trucut biopsy taken and histopathology revealed invasive lobular carcinoma, ER negative, PR moderate positive and HER2 negative
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