Abstract
In an ongoing study of the fate of petroleum hydrocarbons in fish, the authors have examined the petroleum derived metabolites which concentrate in the gall bladder bile of cunners, and rainbow trout. The metabolites obtained from the bile of rainbow trout exposed to a petroleum oil have been analyzed by GLC-MS, and several two- and three-ring aromatic alcohols were identified after hydrolysis with {beta}-glucuronidase. Another approach toward the elucidation of the structure of metabolites derived from No. 2 fuel oil relied on chemical synthesis. In another series of experiments, they investigated the type of metabolites obtained in the bile of trout exposed to three n-alkylbenzenes. Exposure of fish to a mixture containing equal amounts of these three n-alkylbenzenes showed their presence in the bile, in a ratio of 1:3:4, for n-butylbenzene, n-hexylbenzene and n-octylbenzene metabolites, respectively. The present exposure was undertaken to determine if, given aromatic hydrocarbons of same molecular weight and ring structure, a relationship could be found between the type of alkyl side chain and metabolites formed; and the influence of the amount of hydrocarbon administered during an exposure on the type of glucuronides formed. Three structural isomers of butylbenzene were chosen for the present experiment: n-butylbenzene, sec-butylbenzenemore » and tert-butylbenzene.« less
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Bulletin of Environmental Contamination and Toxicology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
