Abstract
Two new 2-benzylbenzofurans, dorsjervin A (1) and dorsjervin B (2), were isolated together with other nine known compounds (3–11) from Dorstenia contrajerva. Structure elucidation of both compounds was done through UV, IR, 1D- and 2D-NMR experiments, and mass spectrometry. All of the isolated compounds were evaluated for an in vitro anti-leishmanial activity; compounds 7 and 8 were active, with IC50’s 4.9 and 2.9μM, respectively. This is the first report on prenylated flavonoids (1, 2, and 7) isolated from a species of Dorstenia in the Americas.
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