Metabolites from the soft coral -associated bacterium \(\textit{Micrococcus}\) sp. strain a-2-28

Abstract

The marine actinomyces Micrococcus was the most common bacterium among the isolates corals, sponges, and alga isolates. Only a few investigations of natural compounds from Micrococcus sp. were reported previously. This study implicated the soft coral-associated Micrococcus sp. strain A-2-28 (following relative Micrococcus flavus LW4T) for large-scale cultivation, chemical analyses, and biological activities. Whereas crude extract of the strain A-2-28 inhibited only Staphylococcus epidermidis, metabolites profiles and pure compounds from strain A-2-28 showed that this strain produced phytohormone (IAA), metabolized some new compounds which were almost inactive for biological tests. This work suggested that it is possible to plan a new strategy for improving coral health and resilience though their associated microbial.