Abstract
The purpose of this study was to present the main events regarding the muscle lactate metabolism to aid the understanding about utilization of the blood lactate concentrations (BLC) on the estimative of lactic anaerobic metabolism and its likely relationship to the acute muscle fatigue. Traditionally, the increase of BLC was associated to the insufficient mitochondrial O2 supply. However, recent studies showed that increase of BLC can be due the action of another agent such as epinephrine and inorganic phosphate. In the same way, the relationship between BLC and acute muscle fatigue has been supported by increase in cellular acidosis. Nevertheless, recent studies have shown that cellular acidosis can restore the force in isolated and electrically stimulated muscle fibers. These findings suggest that utilization of the BLC on the estimative of lactic anaerobic metabolism should be used with caution and the relationship between BLC and acute muscle fatigue can only be a casual phenomenon.
Highlights
The objective of this study was to report the main events involved in muscle lactate metabolism in order to contribute to the understanding of the use of blood lactate concentration (BLC) for the estimation of anaerobic lactate metabolism and their relationship with acute muscle fatigue
Esse modelo teórico foi criado a partir dos resultados de estudos do início do século XVII que demonstraram que a hipóxia ou anóxia induziam a produção do ácido lático (AL)[3]
Utilizando uma atividade intermitente supramáxima realizada com membros inferiores, esses pesquisadores verificaram que o lactato na amostra de sangue arterial do antebraço era significantemente maior após cada estímulo, quando comparado ao venoso
Summary
Rômulo Cássio de Moraes Bertuzzi 1 Adriano Eduardo Lima Silva 1,2 César Cavinato Cal Abad 1 Flávio de Oliveira Pires 1. Recent studies have shown that cellular acidosis is able to partially restore the force of isolated and electrically stimulated muscle fibers These findings suggest that BLC should be used with caution for the estimation of anaerobic lactate metabolism and that the relationship between BLC and acute muscle fatigue is only a casual phenomenon. As concentrações sangüíneas de lactato ([La-]) também são comumente empregadas no estabelecimento da participação do metabolismo anaeróbio lático (MAL) durante o exercício físico, sobretudo, em tarefas que se aproximaram do gesto esportivo como no karatê[5]. Dessa forma, com base nos trabalhos indexados na base Pubmed, os objetivos desta revisão de literatura foram: 1) descrever os principais eventos da produção e da remoção do lactato muscular; 2) apresentar os mecanismos que estabelecem a relação entre o lactato e a fadiga muscular; 3) apresentar a forma de utilização das [La-] na estimativa do metabolismo anaeróbio lático e as suas possíveis limitações
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