Abstract
Intravenously injected C14DTPA in man is quantitatively excreted in urine in 24 hours. Following oral ingestion of C14DTPA, the major portion of the chelate passes unabsorbed through the intestine. However, the presence of the C14 chelate in urine is evidence for absorption of some, although small, amounts of the chelating agents. The metabolism of DTPA was shown to be similar to that of EDTA.
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