Abstract
Considerable recent attention has been focused on the creation of drugs inhibiting the renin-angiotensin system (RAS) of an organism which are advantageous for treating various forms of arterial hypertension. In screening a broad range of derivatives of piperidinecarboxylic acids, cis-l-(3-acetylthiopropionyl)-6-methylpipecolinic acid was found to be the most efficient inhibitor of the RAS and was named METHIAPRIL (I) [ l ]. In the efficacy and duration of action on various models of arterial hypertension, it is close or superior to the foreign antihypertensive drug CAPTOPRIL (II).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
