Abstract

The rate of formation of DNA in regenerating wound tissue of rats was studied by measuring the rate of incorporation of P 32. The most rapid formation of DNA appears to occur during the early stages of wound tissue formation and decreases thereafter. The phosphate pool available to the regenerating tissue remains essentially constant throughout the period studied. It is suggested that changes in rate of DNA synthesis may be due to the different rates of formation of the several types of cells which appear in the tissue at different stages of regeneration.

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