Abstract
The metabolism of isofenphos was examined in adult and larval southern corn rootworm (SCR), Diabrotica undecimpunctata howardi Barber. SCR adults and larvae were analyzed at specific time intervals after treatment with [ 14C]isofenphos at the LD 10 dosage level. Most of the 14C was recovered from the internal organic extract and excreta fractions. The major metabolic pathways of isofenphos in SCR included oxidative desulfuration of isofenphos to isofenphos oxon and hydrolysis of isofenphos oxon and/or parent isofenphos to isopropyl salicylate. Isofenphos penetrated approximately three times faster into larvae than into adults. A lower accumulation of toxic compounds inside the larvae, as a result of a faster metabolism (1.5 ×) and rapid elimination of the parent isofenphos, may explain why larvae are less susceptible than adults.
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