Year-end Sale % OFF 
Abstract
WHEN KNOWN AMOUNTS of crystalline estrogens were incubated with tissue slices in a buffered medium and the mixture was subsequently assayed biologically (I), the following observations were made: a)αcestradiol was completely inactivated by liver tissue, partially inactivated by kidney and not at all by the other tissues tested, b) Estrone was completely inactivated by rabbit liver and only partially inactivated by rabbit kidney and rat liver. Estrone increased in biologic activity, however, after incubation with endometrium, ovary, spleen, heart and lung from the rat and rabbit. This increase in biologic potency of estrone by hese tissues was ascribed to its conversion to αcestradiol by an enzymatic reduction system. The inactivation of estrone and αestradiol by liver and kidney tissue was attributed to an oxidative enzyme
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
