Abstract
1. 1. In vivo experiments in rats showed that D-[1- 14C]galactose was better than D-[1- 14C]glucose as a precursor of D-glucuronic acid, L-gulonic acid and L-ascorbic acid. The conversion of D-[1- 14C]galactose to D-glucuronic acid and L-gulonic acid was demonstrated in rat-liver homogenate. The results presented are in accord with the biosynthesis of L-ascorbic acid via the uridine nucleotides. 2. 2. The administration of barbital to rats stimulated the in vivo conversion of D-[1- 14C]galactose to D-glucuronic acid, L-gulonic acid and L-ascorbic acid. Enhanced formation of D-glucuronic acid from D-[1- 14C]galactose was also observed in liver homogenates from rats pretreated with Chloretone. 3. 3. Formation of D-galacturonic acid from D-galactose in vivo was not detected in rats.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
