METABOLISM OF CREATINE AND CREATININE IN MUSCLE DISEASE

Abstract

Article1 January 1936METABOLISM OF CREATINE AND CREATININE IN MUSCLE DISEASEA. T. MILHORAT, H. G. WOLFF, F.A.C.P.A. T. MILHORATSearch for more papers by this author, H. G. WOLFF, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-7-834 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Excerpt1. Patients with diseases which affect the skeletal muscle commonly have a creatinuria even when they are maintained on a creatine-free diet. Accompanying the creatinuria, there is usually a diminution in the excretion of creatinine and in the ability of the body to retain ingested creatine (a low creatine tolerance).2. In progressive muscular dystrophy, often large amounts of creatine are excreted. The level of the creatinuria and the impairment of the creatine tolerance are usually related to the amount of muscle disability. In advanced stages of the disease the creatine tolerance may be impaired to the extent that all... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Read at the Philadelphia meeting of the American College of Physicians, April 29, 1935.From the New York Hospital and the Department of Medicine, Cornell University Medical College, and the Russell Sage Institute of Pathology, New York, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Biochemistry of Myasthenia GravisBiochemie der progressiven MuskeldystrophieCreatinuria in Patients with palpable muscle affections (Myosis)THE EFFECT OF PARENTERAL INJECTION OF AMINO ACIDS AND RELATED SUBSTANCES UPON CREATINE FORMATION AND STORAGE IN THE RAT 1 January 1936Volume 9, Issue 7Page: 834-837KeywordsCreatineCreatinineDietDisabilitiesExcretionHospital medicineMusclesMuscular dystrophiesSkeletal muscles ePublished: 1 December 2008 Issue Published: 1 January 1936 PDF downloadLoading ...