Abstract
The metabolic fate of 1, N 6-ethenoadenosine ( I) has been studied in rat. The predominant metabolic pathway is the scission of the glycosidic bond in I to yield the free base, 1, N 6-ethenoadenine ( III). Incubation of I with the extract of sarcoma-180 cells in presence of ATP and Mg 2+ did not result in phosphorylation of the nucleoside. No significant uptake of this compound was observed in L-1210 mouse leukemia cells grown in culture.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
