Abstract
When we were working on the partition of nitrogen in the urine of newborn infants, we found that the total N excreted during the first 48 hours of life was of the order of 30 mg/kg of body weight/24 h (Barlow and McCance, 1948). This seemed very small for a human being who was almost starving, for Cathcart (1907) and Benedict (1915) had both obtained figures of the order of 140 mg/kg of body weight/24 h for starving adults. We could not claim that this large difference represented a real difference in the protein catabolized because we knew (McCance and Widdowson, 1947) that the concentration of urea in the body fluids often rose in the three days after birth and unfortunately this was not measured. In following this up, however, observations have been made which seem to be of sufficient interest to bring before you. They may be divided into...
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More From: Cold Spring Harbor symposia on quantitative biology
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