Abstract

ObjectivesThe aim of this study was to examine sex disparity in metabolic syndrome prevalence and its risk factors among Chinese adults.MethodsUsing the 2010–2012 China National Nutrition and Health Survey (CNNHS), a nationally representative cross-sectional study on nutrition and non-communicable chronic diseases, a total of 98,042 participants aged 18 years and older were included in the analysis. Dietary information was collected with a food frequency questionnaire (FFQ). Metabolic syndrome was defined according to the updated NCEP ATP III criteria. A multivariable logistic regression model was performed to examine the associations between sociodemographic and dietary factors with metabolic syndrome prevalence, and the results are presented using odd ratios (ORs) and 95% confidence intervals (CIs).ResultsThe overall standardized prevalence of metabolic syndrome was 24.2% (24.6% in men and 23.8% in women). The metabolic syndrome prevalence was positively associated with age in men and women. The prevalence of metabolic syndrome was negatively associated with the physical activity level among men and inversely associated with the education level among women (P for trend < 0.01). Frequent consumption of fungi and algae was an underlying risk factor for metabolic syndrome in men, whereas frequent consumption of nuts and pork was associated with a decreased prevalence of metabolic syndrome in women.ConclusionsThe prevalence of metabolic syndrome in men was not different from that in women. There are sex-specific associations between multiple risk factors and metabolic syndrome.

Highlights

  • In 2015, approximately 290 million people had cardiovascular disease (CVD)

  • The metabolic syndrome prevalence was positively associated with age in men and women

  • The prevalence of metabolic syndrome was negatively associated with the physical activity level among men and inversely associated with the education level among women (P for trend < 0.01)

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Summary

Introduction

In 2015, approximately 290 million people had cardiovascular disease (CVD). CVD is the number one cause of mortality in China and accounts for over 40% of total deaths [1]. Exploring the cause of metabolic syndrome prevalence may provide important public health implications for the prevention and management of CVD. The prevalence of metabolic syndrome has increased dramatically worldwide [3,4,5]. According to the International Collaborative Study of Cardiovascular Disease in ASIA (InterASIA), the age-standardized prevalence of metabolic syndrome was 13.7% among adults aged 35–74 years in China between 2000 and 2001, using the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria [6]. Based on 2010 China Noncommunicable Disease Surveillance data assessed by NCEP ATP III criteria, the prevalence of metabolic syndrome among participants aged 18 years and older was 33.9% [7]

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