Abstract
We enrolled 103 patients, including 60 males (58.3%) and 43 females (41.7%). The mean age was 32.3±13.3 years (range: 13-65 years). The median Framingham score was 1.2% (IQR=5.8%). Most patients (81.63%) had a low CVR (below 10%) and 18.37% had Framingham score values above 10%. MS and IR prevalences were 16.9% and 61.2%, respectively. CVR in the general population is primarily dependent on age. This observation was valid for our group: the median age was 24 years in people with low CVR, compared with 50 years for those with Framingham score above 10% (p=0.000). None of the antiretroviral drug classes significantly influenced CVR.
Highlights
Most studies published to date have shown an increase in cardiovascular risk (CVR) in patients with HIV infection attributed to both viral activity and antiretroviral therapy (ART)
Our study aimed to evaluate CVR in HIV-infected patients undergoing ART, to identify risk factors for cardiovascular events and to assess the correlations between the presence of Metabolic syndrome (MS), insulin resistance syndrome (IR) and CVR
The presence of MS and CVR were strongly correlated, suggesting that using MS criteria for increased CVR screening is useful in these patients
Summary
Insulin resistance and the risk of cardiovascular disease in HIV patients undergoing antiretroviral therapy. Cătălin Tilişcan1,2*, Victoria Aramă, Raluca Mihăilescu, Daniela Munteanu, Mihaela Rădulescu, Adriana Hristea, Cristina Popescu, Ruxandra Moroti, Violeta Molagic, Raluca Năstase, Ana Maria Tudor, Mihai Lazăr, Anca-Ruxandra Negru, Irina Lăpădat, Mirela Dinu, Adrian Streinu-Cercel, Daniela Adriana Ion, Sorin Ștefan Aramă. From The 9th Edition of the Scientific Days of the National Institute for Infectious Diseases Prof Dr Matei Bals Bucharest, Romania.
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
