Abstract
Aim of work: to study the incidence of components of metabolic syndrome in patients with anal fistulae, to analyze combinations of different components of metabolic syndrome and types of pararectal fistulae.
 Materials and Methods. A clinical examination of 508 patients (85.2% – men; 21.5% at the age of 20-39 years, 43.9% – 40-59 years, 34.6% – ≥60 years) with anal fistulae (of them 48.0% were transsphincteric and 29.3% – extrasphincteric fistulae) who underwent treatment in the department of coloproctology of municipal clinical hospital №5 of Dushanbe in the period from 2010 to 2015, was conducted with the aim of identification of components of metabolic syndrome.
 Results. In 282 patients (55.5% of the total number of patients with anal fistulae, 90.8% of them being men) components of metabolic syndrome were identified: obesity – in 229 patients (45.1% of the total patients with anal fistulae), arterial hypertension – in 115 patients (22,6%), type 2 diabetes mellitus – in 58 patients (11.4%), IHD – in 8 patients (1.6%). In the presence of components of metabolic syndrome the recurrent forms of fistulae were recorded in 16.3% of cases (in the absence – in 12.8% of cases), and complicated forms – extrasphincteric (29.3%) predominated over intrasphincteric forms (22.7%); in control group the proportion of the mentioned forms was 24.8% and 29.2%, respectively. Transsphincteric forms were most common in both groups (48.0% and 46.0%).
 Conclusions. Components of metabolic syndrome in different combinations were identified in more than half (55.5%) the patients with anal fistulae (obesity – 45.1%, arterial hypertension – 22.6%, 2 type diabetes mellitus – 11.4%, IHD – 1.6%). A tendency was recorded to a more common recurrence of anal fistulae and to a more complicated forms of anal fistulae in patients with components of metabolic syndrome.
Highlights
In the presence of components of metabolic syndrome the recurrent forms of fistulae were recorded in 16.3% of cases, and complicated forms – extrasphincteric (29.3%) predominated over intrasphincteric forms (22.7%); in control group the proportion of the mentioned forms was 24.8% and 29.2%, respectively
Transsphincteric forms were most common in both groups (48.0% and 46.0%)
2. У пациентов со свищами прямой кишки из компонентов метаболического синдрома наиболее часто встречается ожирение (45,1%), на втором месте – артериальная гипертензия (22,6%), на третьем – сахарный диабет 2 типа – (11,4%)
Summary
Таджикский государственный медицинский университет имени Абуали ибни Сино, Душанбе, Республика Таджикистан. Проведено клиническое обследование с целью выявления компонентов метаболического синдрома 508 больных (85,2% – мужчины; 21,5% пациентов – в возрасте 20-39 лет, 43,9% – 40-59 лет, 34,6% – ≥60 лет) со свищами прямой кишки (из них транссфинктерные – 48,0%, экстрасфинктерные – 29,3%), которые находились на лечении в отделении колопроктологии городской клинической больницы No5 г. У 282 человек (55,5% от общего количества пациентов со свищами прямой кишки, из них 90,8% – мужчины) выявлены компоненты метаболического синдрома, в том числе: ожирение – у 229 человек (45,1% от общего количества наблюдаемых пациентов со свищами прямой кишки), артериальная гипертензия – у 115 человек (22,6%), сахарный диабет 2 типа – у 58 человек (11,4%), ИБС – у 8 человек (1,6%). Более чем у половины пациентов (55,5%) со свищами прямой кишки выявлены компоненты МС в различных сочетаниях (ожирение – 45,1%, артериальная гипертензия – 22,6%, сахарный диабет 2 типа -11,4%, ИБС – 1,6%).
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