Abstract
Objective: To determine the prevalence of metabolic syndrome (MetS) in patients of acute coronary syndrome. Methodology: This cross-sectional study was conducted in department of cardiology, CPE institute of cardiology Multan. A total of 150 patients of ACS who were admitted in the hospital from Oct-2018 to March-2019 were included. Patients demographics, reason for admission in hospital were noted. Waist circumference, body mass index (BMI), serum lipid profile, and fasting blood sugar was measured in all patients. Results: Metabolic syndrome (MetS) was diagnosed in 53 (35.3%). Frequency of heart failure was lower in Non-MetS group; 17 (17.5%) versus 15 (28.3%) in MetS group (p-value 0.12). STEMI was 10 (18.8%) in MetS group whereas it was 28 (28.8%) in Non-MetS group (p-value 0.18). Arrhythmias occurred in 5 (9.4%) in MetS group; as compared to 5 (5.15%) in Non-MetS group (p-value 0.32). Conclusion: The prevalence of MetS in present study was 35.3% and these patients were mostly female and obese. These were more likely admitted because of heart failure and arrhythmias. Key Words: Metabolic syndrome, Acute coronary syndrome, heart failure, myocardial infarction
Highlights
Coronary artery disease (CAD) is associated with highest mortality worldwide.[1]
Metabolic syndrome (MetS) was diagnosed in 53 (35.3%). frequency of heart failure was lower in Non-metabolic syndrome (MetS) group; 17 (17.5%) versus 15 (28.3%) in MetS group (p-value 0.12)
Serum lipid profile was measured after 12 hours fasting, and blood pressure of all patients was measured in lying position using digital sphygmomanometer
Summary
Coronary artery disease (CAD) is associated with highest mortality worldwide.[1] Atherosclerosis is the major cause of CAD and is a major risk of premature deaths.[2] Current evidence have supported that cardio-vascular risks starts to develop in early life and are responsible for 2% to 10% all cases of CAD in young adults.[2,3] Risk of CAD in Asia is 50 to 300 times higher as compared to the western world.[4] CAD has a major burden in Pakistani population and more than 30% of patients of age greater than 45 years suffer from CAD in Pakistan.[5] According to WHO, CAD has become the biggest cause of death in Pakistan.[6]
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