Abstract
Introduction: The metabolic syndrome is a clinical entity defined by the association in the same subject of four of the following five factors: abdominal obesity (or android), type 2 diabetes, hypertension, hypo HDL cholesterolemia, hypertriglyceridemia. The aim of the work was to study the epidemiological, clinical-biological profiles and complications of patients in the cardiology and internal medicine department of the Mother-Child CHU “Luxembourg”. Materials and Methods: We carried out a cross-sectional study, from September 2019 to June 2020 in the cardiology and internal department of the mother-child CHU “Luxembourg”. All patients with metabolic syndrome admitted to the two departments who agreed to participate during the study period were included in the study. These patients meet the 2009 harmonization attempt criteria (IDF 2009). The variables studied were: socio-demographic characteristics (sex, age, profession), pathological history, clinical signs (functional signs, BMI, waist size), paraclinical signs (ECG, cardiac ultrasound, laboratory assessment) and complications. Results: A total of 104 patients were included. The female sex represented 58.65% of cases. The 60 to 69 age group was the majority with 40.78%, housewives occupied 41.34% of cases. Diabetes, arterial hypertension and dyslipidemia were the most represented cardiovascular risk factors with respectively: 80.77%, 79.81% and 53.85%. Visual blurring was the most common functional sign with 23.08% of cases. Moderate obesity was observed in 34% of patients. Waist circumference was high in 39.53% of male patients and 37.70% of female patients. Cardiac ultrasound found a severely collapsed ejection fraction in 25% of patients. HDL-c levels were low in 64.52% of male patients and 75% of female patients. The most observed complications were: dyslipidemia (53.85%), stroke and renal failure with 23% respectively. Conclusion: The metabolic syndrome remains a real public health problem, constantly increasing in our populations and constitutes a danger by its constituent elements.
Highlights
The metabolic syndrome is a clinical entity defined by the association in the same subject of four of the following five factors: abdominal obesity, type 2 diabetes, hypertension, hypo HDL cholesterolemia, hypertriglyceridemia
All patients with metabolic syndrome admitted to the two departments who agreed to participate during the study period were included in the study
The metabolic syndrome is a real public health problem because of its complications, the absence of data at the level of the Mother-Child University Hospital “Luxembourg” motivated us to carry out this work with the aim of studying the epidemiological, clinical-biological profiles and the related complications in the cardiology and medicine department at the Mother-Child University Hospital “Luxembourg” in Bamako
Summary
The metabolic syndrome is a clinical entity defined by the association in the same subject of four of the following five factors: abdominal obesity (or android), type 2 diabetes, hypertension, hypo HDL cholesterolemia, hypertriglyceridemia. Since its initial description by REAVEN in 1988 under the term “syndrome X”, the metabolic syndrome has continued to evolve and several definitions are currently proposed [2] It is characterized by hyperinsulinism resulting from insulin resistance and a group of factors including hypertriglyceridemia, hypo HDL cholesterolemia, glucose intolerance, high blood pressure and android obesity [1]. The metabolic syndrome is a real public health problem because of its complications (cardiovascular and type 2 diabetes), the absence of data at the level of the Mother-Child University Hospital “Luxembourg” motivated us to carry out this work with the aim of studying the epidemiological, clinical-biological profiles and the related complications in the cardiology and medicine department at the Mother-Child University Hospital “Luxembourg” in Bamako
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