Abstract

Background: Metabolic syndrome is a cluster of metabolic risk factors for type 2 diabetes mellitus and cardiovascular diseases. Physiological variations occurring in women during menopause are thought to be a predisposing factor for the metabolic syndrome. The aim of this study was to evaluate the prevalence of metabolic syndrome and its individual components according to menopausal status in a sample of Moroccan women. Methods: We analyzed data of 653 women aged 19 years and older. We used the recently published joint interim statement criteria to classify subjects as having metabolic syndrome. Results: Out of the total subjects, 262 (40.12%) were syndromic. The metabolic syndrome and abdominal obesity were more common in postmenopausal than in premenopausal women. The highest prevalence of metabolic syndrome was observed in menopausal transition especially among women aged 49-52 years (62.59%). During this period, half of women have at least three metabolic syndrome risk factors. Conclusion: Abdominal obesity associated with metabolic changes occurring in menopause was a risk factor for the development of metabolic syndrome in women. There is a need to adopt a healthy lifestyle to prevent weight gain in women. This can minimize the incidence of metabolic syndrome and its consequences as type 2 diabetes and cardiovascular diseases.

Highlights

  • Metabolic syndrome is a group of interrelated risk factors of metabolic origin that appear to directly advance the growth of atherosclerotic cardiovascular disease and type 2 diabetes mellitus [1,2]

  • Prevalence of metabolic syndrome and abdominal obesity were more common in women in postmenopause than in premenopause. (Table 2)

  • Our findings show that the prevalence of metabolic syndrome in Moroccan women has changed according to the menopausal status, becoming higher in postmenopausal women (45.08%) than those in the premenopause (32.96 %), (P

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Summary

Introduction

Metabolic syndrome is a group of interrelated risk factors of metabolic origin that appear to directly advance the growth of atherosclerotic cardiovascular disease and type 2 diabetes mellitus [1,2]. Studies showed that metabolic syndrome is associated with a threefold increased risk of coronary heart disease, myocardial infarction, and stroke [4], and a three- to fivefold increased risk of cardiovascular death [5,6] even after adjustment for conventional risk factors [7]. The highest prevalence of metabolic syndrome was observed in menopausal transition especially among women aged 49-52 years (62.59%). There is a need to adopt a healthy lifestyle to prevent weight gain in women This can minimize the incidence of metabolic syndrome and its consequences as type 2 diabetes and cardiovascular diseases.

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