Metabolic syndrome and insulin resistance in college students from central Mexico (641.14)

Abstract

Many epidemiologic studies have been focused on the estimation of metabolic syndrome (MS) in adults. Some of them have included the quantification of insulin resistance (IR) through the Homeostasis Model Assessment (HOMA‐IR). The objective of this cross‐sectional study was to evaluate the prevalence of MS in 776 students from Querétaro (central Mexico), aged 17‐29 years. Conventional methods were used to measure body weight, height and, waist circumference and blood pressure. After 12‐hour fasting period, a blood sample was taken to analyze glucose (Glc), total cholesterol, HDL‐cholesterol, triglycerides (TG) and insulin concentrations. LDL‐cholesterol and HOMA‐IR were estimated. Obesity and overweight were presented in 25% of the participants. Average waist circumference was higher in men tan in women (73.4±0.5 vs. 80.2±0.6 cm). Glc, TG and blood pressure were significant higher in men (P<0.0001). The prevalence of MS using the Adult Treatment Panel (ATP III) criteria was 12% and 72% of the students had at least one component of MS. TG and HDL‐cholesterol were the biochemical markers mainly associated with MS. TG concentrations were three times higher in students with 3 risk factors of MS compared to those students without any risk factor. IR was present in 43% of students, with mean HOMA‐IR of 3.6 ± 2.6. IR was observed even in students with normal glucose. IR has to be used together with the detection of MS in young students, to prevent further health problems.Grant Funding Source: Supported by PIFI‐FCN 2012