Abstract

Objective: The present study was designed to estimate the prevalence of metabolic syndrome and evaluate other associated risk factors among hypertensive adults of the southern part of Rajasthan, India. Design and method: A total of 2100 hypertensive patients were interviewed using a pretested and validated questionnaire about lifestyle practices and medical history. The diagnosis of Metabolic Syndrome (MS) was done using National Cholesterol Education Program – Adult Treatment Panel III criteria with an anthropometric modification of waist circumference (WC) value that is specifically applicable to South Asians. Hypertension (HTN) was diagnosed with BP over 130 and/or > 85 mm Hg, abdominal obesity (AO) according to waist circumstance (WC) > 90/80 cm men/women, hypertriglyceridemia (HTG) > 150 mg/dl, hyperglycemia > 110 mg/dl, decreased HDL < 40/50 mg/dl for men/women. Biochemical parameters (lipids and glucose) were measured using sphectrometry on COBAS (ROCHE) equipment. All calculations and statistical analyzes are processed by the SPSS 21.0. Results: The study subjects were 58% males and 42% females, with a mean age of 46.21 ± 9.40 years. Abdominal obesity was found in 57.3%, HTG 31.8%, hyperglycemia 32.6%, decreased HDL 29.2%, MS 31.4%. Diabetes prevalence was found to be 21.2% including 17% of known cases and 4.2% of new cases. Regarding the risk factors, 28.7 % were tobacco smokers; Physical inactivity 49%, more frequent in men than women (p = 0.04); Abdominal obesity was significantly higher in women; diabetes was associated with abdominal obesity and dyslipidemia in 59% of cases; 67.8% of subjects had at least three associated risk factors. Conclusions: Indian subcontinent has highest rates of CVDs worldwide. This study reveals high prevalence of metabolic syndrome as well as other risk factors. It is necessary to do nation wide surveys to formulate effective preventive strategies.

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