Abstract
Potential associations among glucose tolerance test (GTT) as ability to metabolize glucose, estimated breeding values (EBVs) for milk traits and selected candidate gene polymorphisms were evaluated. German Holstein sires, born in 1993 and between years 1999 and 2003, were analysed. A few significant negative correlations between milk and protein yield and GTT were found in sires born in 1993. Only a few significant correlations were found for protein yield, protein percentage and for fat percentage and yield (sires born in different years). Any linkage of DGAT1, GH1, GHR, FASN and OLR1 to GTT was found. Keywords: milk, glucose, correlation, breeding values References Deepa, P.M . et al. (2015) Alteration in clinico-biochemical profile and oxidative stress indices associated with hyperglycaemia with special reference to diabetes in cattle-a pilot study. Trop. Anim. Health Prod. , Vol. 47, no. 1, pp. 103-109. DOI:10.1007/s11250-014-0691-5 Di Stasio, L. et al. (2005) Polymorphism of the GHR gene in cattle and relationships with meat production and quality. Anim. Genet. , Vol. 36, pp. 138–140. Grisart, B. et al. (2002) Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition. Genome Res., Vol. 12, pp. 222-231. Kneeskern, S. G . et al. (2016) Effects of chromium supplementation to feedlot steers on growth performance, insulin sensitivity, and carcass characteristics. J. Anim. Sci. , Vol. 94, no. 1, pp. 217-226. DOI: 10.2527/jas2015-9517 Khatib, H. et al. (2006) Association of the OLR1 Gene with Milk Composition in Holstein Dairy Cattle. J. Dairy Sci. , Vol. 89, pp. 1753–1760. Morris, C. A. (2007) Fatty acid synthase effects on bovine adipose fat and milk fat. Mamm. Genome , Vol. 18, pp. 64–74. Panicke, L. et al. (2000) Relationships between parameters of the glucose tolerance test by young sires and estimated their breeding values. Arch. Tierz. , Vol. 43, pp. 231-239.
Highlights
Energy metabolism plays an important role in production of healthy animals with high performance as the goal of cattle breeding
The aim of this study was to evaluate the relationship between glucose tolerance test (GTT) and breeding values for milk performance
Other candidate gene associated with milk production is oxidized low-density lipoprotein receptor (OLR1) with final effect on the milk composition (Khatib et al, 2006)
Summary
Energy metabolism plays an important role in production of healthy animals with high performance as the goal of cattle breeding. Only a few studies focused on association of GTT results to milk performance (Panicke et al, 2000). The aim of this study was to evaluate the relationship between GTT and breeding values for milk performance. We analysed the association among GTT and several candidate genes. We selected candidate genes with association with milk performance. DGAT1 is a candidate gene for milk fat (Grisart et al, 2002). With potential affect on milk production, are genes for growth hormone (GH1) and its receptor (GHR) (DiStasio et al, 2005). Other candidate gene associated with milk production is oxidized low-density lipoprotein receptor (OLR1) with final effect on the milk composition (Khatib et al, 2006). Fatty acid synthase (FASN), which SNP are associated with variations in fatty acid composition, was selected (Morris et al, 2007)
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