Abstract
Paper chromatography was carried out on the urine of rabbits and men receiving 1-ethynylcyclohexyl carbamate. The chromatogram revealed the presence of six spots by the Tollens reagent and three of them were assumed to be the metabolites, degradation products of the carbamate. One of them was identified as the hydroxylated ethynylcyclohexyl carbamate which was also obtained by extraction of the urine of man receiving 1-ethynylcyclohexyl carbamate. Another spot on the chromatogram was assumed to be that of a conjugated form of the metabolite such as the glucuronide which had been reported by McMahon.
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