Abstract
Introduction: Apart from its well known function in the central nervous system corticotropin releasing hormone (CRH) seems to have an additional role in peripheral tissues. Besides in the myocardium and skin, CRH receptors (CRH-R) have also been found in human adipose tissue and intravenous administration of CRH in humans leads to an increase of energy expenditure and fatty acid oxidation. In order to further clarify the role of CRH in adipose tissue we investigated changes in adipose tissue metabolites and blood flow after injection of CRH in humans.
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