Abstract
THE production of a diabetic state in normal people by administration of ACTH has been demonstrated (1). In patients with diabetes mellitus administration of ACTH has been shown to result in a marked rise of blood sugar (2), and administration of cortisone has produced intensification of glycosuria and increased requirements for insulin (3, 4). An increase in excretion of ketone bodies occurs in patients with combined Addison's disease and diabetes mellitus when cortisone is given (5). A study of the metabolic effects of ACTH given over a prolonged period of time to a patient with diabetes mellitus has not been reported. Although important, such an experiment is not justifiable in a patient with uncomplicated diabetes mellitus because of the danger of permanent intensification of the diabetic state. Recently the opportunity arose to study a patient with diabetes mellitus of long standing, who received a twenty-two-daycourse of ACTH in the hope of arresting a progressive subacute myelogenous leukemia. The ...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: The Journal of clinical endocrinology and metabolism
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
