Abstract
BackgroundA study was conducted to investigate changes in oxidative stress indicators of West African dwarf (WAD) goats at different reproductive stages. There are a total of 35 dry does, 30 gravid does at first trimester (40–45 days post-mating), 33 gravid does at second trimester (85–90 days post-mating), 31 gravid does at third trimester (135–140 days post-mating), and 40 postpartum does (30–35 days postpartum). Fastened blood samples were collected from all tagged animals and serum obtained. Serum was assayed for lipid peroxidation, total antioxidant activity, glutathione peroxidase, catalase and superoxide dismutase, serum biochemical, glucose, total protein, albumin, cholesterol, triglyceride, high-density lipoprotein, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, urea, and creatinine using standard procedures.ResultsResult revealed that intense metabolic changes were associated with late prepartum and postpartum does as pronounced in oxidative and biochemical indicators of WAD does. Significant differences were found in serum biochemical indices across the different physiological stages of the doe except for triglyceride and low-density lipoprotein. Antioxidant defense is higher at early and mid-gestation and dry does, through low lipid peroxidation and high antioxidant activity as compared to late gestation and lactation does.ConclusionThe observed result shows that the WAD does display oxidative stress during late gestation and lactation owing to intense metabolism. Antioxidant fortification should be employed especially during late gestation and lactation to counteract the oxidative stress in WAD goats.
Highlights
A study was conducted to investigate changes in oxidative stress indicators of West African dwarf (WAD) goats at different reproductive stages
This study aims to document the baseline range of oxidative stress markers and requirements for antioxidant defense at different physiological stages of West African dwarf does
Body condition score (BCS), usually a visual assessment of the amount of fat and muscle covering the bones of a goat, evaluates fatness or thinness according to a 5-point scale, where BCS 1—very thin, BCS 2—thin, BCS 3—good condition, BCS 4—fat, and BCS 5—obese (Ockert 2015)
Summary
A study was conducted to investigate changes in oxidative stress indicators of West African dwarf (WAD) goats at different reproductive stages. Fastened blood samples were collected from all tagged animals and serum obtained. The West African dwarf (WAD) goats are found in the region south of latitude 14° N across West Africa in the coastal area, which is humid and favors high prevalence of diseases. The harsh environmental conditions of the tropics in which the animals are exposed to are further aggravated by the seasonal fluctuations in quantity and quality of most of the feed resources which they. Only a limited number of physiological status have been investigated with regard to the effects of oxidative stress in ruminants (Celi 2011a). Only a limited number of physiological status have been investigated with regard to the effects of oxidative stress in ruminants (Celi 2011a). Jack et al (2016) suggested the relevance of periodic assessment of oxidative status in ruminants for healthier management and supplementation of antioxidants as supportive treatment of diseases such as peste des petits ruminants (PPR). Ihejirika et al (2017) reported emphasis should be on antioxidant activity of does with different physiological stages, so as to improve
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