Abstract
The number of people receiving renal replacement therapy (RRT), through either dialysis or renal transplantation, exceeds 2.5 million worldwide and its prevalence is expected to rise sharply over the next decades. The predicted growth in prevalence of end-stage kidney disease (ESKD) demonstrates a need for initiatives that will slow the progression to ESKD in Chronic Kidney Disease (CKD) and preserve quality and quantity of life from those on dialysis. For more than a century, metabolic acidosis has been recognized as [...]
Highlights
Metabolic acidosis is defined as serum bicarbonate levels that are persistently less than 22 mEq/L5
Clinical guidelines for the management of Chronic Kidney Disease (CKD) recommend the treatment of metabolic acidosis with oral alkali[6]
Studies have shown that metabolic acidosis is the most common acid-base abnormality found in this population
Summary
Metabolic acidosis is defined as serum bicarbonate levels that are persistently less than 22 mEq/L5. Clinical guidelines for the management of CKD recommend the treatment of metabolic acidosis (serum bicarbonate
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