Abstract
PURPOSE: Postextubation stridor can prolong ICU stay and increase mortality rate. This arises from the reactive edema in the glottic or subglottic mucosa from pressure of the endotracheal tube. Intubated patients with cuff leak volume above 25% of the tidal volume are at high risk for postextubation stridor. The use of corticosteroids may offer protection because of their anti-inflammatory effects. Corticosteroids, however, may cause adverse effects hence a more systematic assessment of its efficacy is warranted prior to adoption of this practice. This study aims to determine whether prophylactic use of systemic corticosteroids prevents postextubation stridor and subsequent reintubation from laryngeal edema. It also aims to site the deleterious effects of this recommendation.
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