Meta-analysis of clinical efficacy of laparoscopic surgery for hepatic cystic echinococcosis

Abstract

Objective To investigate the clinical efficacy and safety of laparoscopic surgery in the treatment of hepatic cystic echinococcosis. Methods Literatures published from January 1992 to November 2017 were retrieved in database of PubMed, Cochrane Library and Wanfang data, etc. The searching keywords included hepatic cystic echinococcosis, echinococcosis, surgery, laparoscope, minimally invasive surgery, living or hepatic, open, laparoscopic or minimal invasive in both Chinese and English. Clinical data related to therapeutic effect, complications, length of hospital stay and recurrence rate were extracted for Meta-analysis from the included literatures. Results A total of 8 articles were eligible including 6 retrospective case-control studies and 2 prospective studies. A total of 1 075 cases were recruited including 238 cases in laparoscopic surgery group and 837 in open surgery group. In laparoscopic surgery group, the incidence of postoperative complications was significantly lower (OR=0.58, 95%CI: 0.38-0.87, P 0.05). Conclusions Laparoscopic surgery is safe for cystic echinococcosis, it can achieve the same effect as open surgery. Compared with open surgery, laparoscopic surgery has the advantages of lower incidence of postoperative incision-related complications and shorter length of hospital stay. Key words: Echinococcosis, hepatic; Laparoscopes; Surgical procedures, operative; Comparative effectiveness research; Perioperative care