Abstract
BackgroundWe undertook a meta-analysis to evaluate the accuracy of 18FDG PET-CT for diagnosis of distant metastases in lung cancer patients. MethodsStudies about 18FDG PET-CT for diagnosis of distant metastases in patients with lung cancer were systematically searched in the MEDLINE and EMBASE databases. We calculated sensitivities, specificities, positive likelihood ratios and negative likelihood ratios, and constructed summary receiver operating characteristic curves using bivariate regression models for 18FDG PET-CT. ResultsAcross 9 studies (780 patients), the sensitivity, specificity, positive likelihood ratio and negative likelihood ratio of 18FDG PET-CT were 0.93 (95% confidence interval [CI] = 0.88–0.96), 0.96 (95% CI = 0.95–0.96), 28.4 (95% CI = 14.0–57.5), and 0.08 (95% CI = 0.02–0.37), respectively. Overall weighted area under the curve was 0.98 (95% CI = 0.96–0.99). Conclusion18FDG PET-CT has excellent diagnostic performance for diagnosis of distant metastases in patients with lung cancer.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
