Meta-Analysis on the Clinical Outcomes of Transcatheter Aortic Valve Implantation in Low-Surgical Risk Patients With Bicuspid Aortic Valves

Abstract

Transcatheter aortic valve implantation (TAVI) has been widely considered for patients with aortic stenosis (AS) across all surgical risk spectra.1 Bicuspid aortic valve (BAV) is the most common congenital heart defect and can progress to moderate to severe AS in about 12% to 37% of affected patients.2 Patients with BAV have traditionally been excluded from trials comparing TAVI and surgical aortic valve replacement, mainly due to their complex valvular anatomy and higher incidence of postprocedural paravalvular leak (PVL).