Meta analysis on curative effect of percutaneous vertebral plasty for spinal metastasis

Abstract

Objective To systematically evaluate the efficacy of percutaneous vertebral plasty in the treatment of spinal metastatic tumors. Methods The databases of PubMed, Science Direct Online, Springer, CNKI, Wanfang, and Vip were retrieved, and the relevant clinical studies were collected. After the two researchers had screened the literatures, the data were extracted and the quality was evaluated according to the inclusion and exclusion criteria. The Meta analysis was carried out using Stata 12.0 software. Results 33 clinical studies were included, with a total of 1 727 patients and 2 546 vertebral bodies. The Meta analysis showed that there were statistical differences in VAS score 1 week and 1 and 3 months after operation (P<0.05). The average rate of intraoperative bone cement leakage was 21%, and the average rate of life improvement after operation was 85%. Conclusions Percutaneous vertebral plasty, as a minimally invasive procedure, can relieve refractory pain caused by spinal metastasis in the early stage and long-term, and can improve the life quality in patients with malignant tumors. Key words: Percutaneous vertebral plasty; Spinal metastasis; Meta analysis