Abstract
ObjectiveThis study aimed to systematically evaluate the factors influencing the restoration of spontaneous circulation (ROSC) after cardiopulmonary arrest (CA).MethodsRelevant papers on the factors influencing the ROSC in patients with CA were retrieved from PubMed, Embase, Cochrane Library, China Biology Medicine disk, China National Knowledge Infrastructure, Wanfang, and VIP databases. After screening, data extraction, and quality evaluation of the papers, a meta-analysis was carried out.ResultsA total of 36 papers, involving a total sample size of 2,305 cases, were included. The meta-analysis revealed that the location and time of onset of CA, the type of cardiac rhythm at first monitoring, the start time of cardiopulmonary resuscitation (CPR), the use of electric defibrillation, and the cumulative dose of adrenaline all significantly impacted the ROSC (p < 0.05) and may have affected its success rate. The pH value at CA onset, combined use of adrenaline and vasopressin, CPR duration, mechanical cardiac compression use, and whether CA was caused by heart disease had no significant effect on ROSC.ConclusionThe location and time of onset of CA, the cardiac rhythm at first monitoring, the start time of CPR, the use of electric defibrillation, and the cumulative dose of adrenaline significantly impacted the ROSC.
Highlights
Cardiopulmonary arrest (CA) is a common acute and critical illness in which the heartbeat ceases without warning and the patient suddenly stops breathing
This study systematically evaluated the factors influencing the ROSC in patients with CA to provide a reference point for future treatment
The meta-analysis revealed that, compared with out-of-hospital CA, the risk ratio (RR) for the ROSC in the hospital was 3.59, and compared with CA at night, the RR for the ROSC during the day was 1.40
Summary
Cardiopulmonary arrest (CA) is a common acute and critical illness in which the heartbeat ceases without warning and the patient suddenly stops breathing. There is a sudden loss of consciousness, respiratory arrest, or weak, sigh-like breathing, and no pulse can be felt. Cardiopulmonary resuscitation (CPR) is an important measure used to treat CA. CPR and other advanced recovery technologies are improving, the restoration of spontaneous. Factors Influencing the ROSC circulation (ROSC) rate is still very low (Tang et al, 2017). This study systematically evaluated the factors influencing the ROSC in patients with CA to provide a reference point for future treatment
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