Meta-analysis of quadratus femoris muscle pedicle bone flap transplantation in the repair of femoral neck fracture for young and middle-aged patients

Abstract

Objective To compare the efficacy of quadratus femoris muscle pedicle bone flap transplantation combined with hollow compression screw fixation versus hollow compression screw fixation in the repair of femoral neck fracture for young and middle-aged patients. Methods Case-controll studies comaring the quadratus femoris muscle pedicle bone flap transplantation with hollow compression screw fixation in the repair of femoral neck fracture were retrieved from CNKI, Chinese Biomedical Database, Wanfang Data and manually (from January, 2005 to December, 2014). Methodological quality of the trials was critically assessed, and relevant data were extracted. Statidtical software Revman 5.0 was used for data-analysis. Results Eight articles were included in the meta-analysis. The results showed that, compared the efficacy of quadratus femoris muscle pedicle bone flap transplantation combined with hollow compression screw fixation with hollow compression screw fixation,there were statidtical significance in the rate of fracture healing [OR= 5.43, 95%CI(2.89, 10.20), P < 0.05], the rate of good function of hip joint [OR= 5.12, 95%CI(3.21, 8.17), P < 0.05], the rate of femoral head necrosis [OR= 4.21,95%CI(2.02,8.76), P < 0.05], the time of fracture healing [WMD=-46.85, 95%CI(-65.13, -28.56), P < 0.05]. Conclusion The transplantation of quadratus femoris muscle pedicle bone flap combined with hollow compression screw fixation is superior to the hollow compression screw fixation in the repair of femoral neck fracture for young and middle-aged patients in regards to the rate of fracture healing, the rate of good function of hip joint, the rate of femoral head necrosis, the time of fracture healing. Key words: Femoral neck fracture; Quadratus femoris muscle pedicle bone flap; Hollow compression screw fixation; Meta-analysis