Abstract
ABSTRACT Selenium-based feed supplement is essential for increasing the performance of aquatic organisms. This study aims to analyze and evaluate various data on selenium supplementation in freshwater fish feed by meta-analysis with mixed-model. The study used secondary data from the literature database. Total 27 references containing 125 treatments were analized. Using linear and quadratic regression equations, selenium supplementation in freshwater fish feed resulted in a significantly increased final body weight, weight gain, feed intake, and protein efficiency ratio (P < .05). Then, the GPx activity enzyme in the liver and the increased high-density lipoprotein (HDL) content in the blood of fish exhibited a favorable trend with significantly higher value (P < .05) compared to control fish. However, selenium supplementation could significantly reduce total protein, globulin, low-density lipoprotein (LDL) and cholesterol levels (P < .05). This study concluded that organic selenium supplementation in the range of 0.95 to 6.8 mg/kg feed could improve freshwater fish’s performance.
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