Meta-analysis of factors influencing quality of life in children and adolescents with type 1 diabetes mellitus

Abstract

Objective Evaluate the main factors affecting the quality of life of children and adolescents with type 1 diabetes. Methods The System retrieval from the establishment of the library to March 19, 2019 in the Chinese journal full-text database, China Biomedical Literature Database, Weipu Journal Full Text Database, Wanfang database, PubMed, Webscien database on the study of factors affecting the quality of life of children and adolescents with type 1 diabetes, using RevMan5.3 and Stata12.0 software, used the inclusion of the literature Meta analysis. Results According to the inclusion and exclusion criteria, a total of 17 documents were included, with a total sample size of 11266 cases. The combined effect of the effect sage factors of quality of life in children and adolescents with type 1 diabetes and 95% CI were gender 0.31 (0.20-0.42), age 0.22 (0.08-0.36), age of onset 0.07 (0.01 - 0.12), and whether it was an only child 0.62 (0.33 - 0.91), household annual income - 0.45 (-0.66 -- 0.24), blood sugar control 0.66 (0.50 - 0.82), number of insulin injections per day -0.22 (-0.39 --0.04), HbA1c0.39 (0.33 - 0.46). Conclusion Gender, age, age of onset, household annual income, blood sugar control, number of insulin injections per day, HbA1c were the main factors affecting the quality of life of children and adolescents with type 1 diabetes. To provide reference for hospitals, families, communities, schools to take a variety of practical measures. Key words: T1DM; Quality of life; Influence factors; Met-analysis